Africa is home to many small, isolated economies, an economic geography that presents severe handicaps. Regional integration can break that isolation, providing larger and more competitive markets, lowering prices for food, power, industrial inputs; and harmonizing customs and other administrative procedures that presently raise the costs of traded goods. Integrating physical infrastructure is an essential precursor for deeper integration. Chapter 6 identifies the benefits of regional integration across the infrastructure sectors and documents the institutional challenges that stand in the way, such as building political consensus, establishing effective regional institutions, prioritizing regional investments, and facilitating cross-border finance.